姓名：连超群，性别，职称：教授，学历，博士，毕业院校江苏大学，工作单位生物化学与分子生物学教研室，呼吸系疾病安徽省重点实验室，临床检验诊断中心，学术领域：肿瘤分子生物学，研究方向：肿瘤生物信息学、肿瘤网络药理学领域
一、科研成果
l 科研项目：
⑴.呼吸系病临床基础安徽省重点实验室开放课题（HX2023D02）：精氨酸代谢基因SMS促进肺腺癌进展及调控代谢重编程和肿瘤微环境的机制研究， 导向性项目 呼吸系病临床基础安徽省重点实验室，2024.1-2025.12 ，10万元、主持。
⑵安徽省教育厅自然科学研究重点项目（KJ2021A0773）： FAF2在Orlistat调控肿瘤细胞铁死亡中的作用及机制研究，2022.1-2023.12、6万元、主持。（
l 论文发表
1.Dong, X., T. T. Zhang, C. Y. Gui, S. P. Fei, H. A. Xu, J. R. Chang, C. Q. Lian, and W. G. Tang. 2024. ' The critical role of residues Phe120 and Val161 of (2 R,3 R)-2,3-butanediol dehydrogenase from Neisseria gonorrhoeae as probed by molecular docking and site-directed mutagenesis', J Basic Microbiol, 64.（通讯作者）
2.Lian, C. Q., Y. L. Huang, P. Hu, Y. C. Cao, Z. Q. Zhang, F. Feng, and J. Zhang. 2023. 'Nitidine Chloride Triggers Autophagy and Apoptosis of Ovarian Cancer Cells through Akt/mTOR Signaling Pathway', Curr Pharm Des, 29: 1524-34. （第一作者）
3.Lian, C. Q., F. F. Li, Y. L. Xie, L. X. Zhang, H. L. Chen, Z. Q. Wang, X. Y. Pan, X. J. Wang, and J. Zhang. 2024. 'Identification of T-cell exhaustion-related genes and prediction of their immunotherapeutic role in lung adenocarcinoma', J Cancer, 15: 2160-78. （第一作者）
4.Ma, H. Y., J. Zhang, Y. Shi, Z. Q. Wang, W. H. Nie, J. J. Cai, Y. L. Huang, B. Liu, X. J. Wang, and C. Q. Lian. 2023. 'PBK correlates with prognosis, immune escape and drug response in LUAD', Scientific Reports, 13. （通讯作者）
5.Min, S. P., L. Y. Wang, Y. L. Xie, H. L. Chen, R. J. Wang, G. Song, X. J. Wang, and C. Q. Lian. 2024. 'Copper-binding protein modelling by single-cell transcriptome and Bulktranscriptome to predict overall survival in lung adenocarcinoma patients', J Cancer, 15: 2659-77. （通讯作者）
6.Sun, K., D. Q. Wang, Z. Q. Zhang, Y. L. Huang, X. F. Lian, J. L. Hua, J. Zhang, and C. Q. Lian. 2023. 'Columbianetin acetate inhibits the occurrence and development of pancreatic cancer cells by down-regulating the expression of Meiotic nuclear divisions 1', Biocell, 47: 297-307. （通讯作者）
7.Sun, K., Z. Q. Zhang, D. Q. Wang, Y. L. Huang, J. Zhang, and C. Q. Lian. 2023a. 'B cell-related tertiary lymphoid structure may exert inhibitory effects on lung adenocarcinoma and SARS-COV-2', Heliyon, 9. （通讯作者）
8.Sun, K., Z. Q. Zhang, D. Q. Wang, Y. L. Huang, J. Zhang, and C. Q. Lian.. 2023b. 'Regulation of early diagnosis and prognostic markers of lung adenocarcinoma in immunity and hypoxia', Scientific Reports, 13. （通讯作者）
9.Tian, H. J., A. M. Chen, P. Y. Gao, F. F. Wang, Y. M. Zhao, F. C. Wang, C. Q. Lian, and Q. Zhang. 2024. 'Human Umbilical Cord Mesenchymal Stem Cell-derived Exosomes Induce Macrophage M2 Polarization by Antagonizing LPS-mediated Stimulation of the NF-κB and STAT3 Pathways', Combinatorial Chemistry & High Throughput Screening. （通讯作者）
10.Wang, D. Q., Y. Shi, Z. Q. Wang, J. Zhang, L. Y. Wang, H. Y. Ma, S. H. Shi, X. F. Lian, H. Huang, X. J. Wang, and C. Q. Lian. 2024. 'Meiotic nuclear divisions 1 suppresses the proliferation and invasion of pancreatic cancer cells via regulating H2A.X variant histone', Biocell, 48: 111-22.
二、研究方向
肿瘤生物信息学、网络药理学等领域
三、指导学生情况：
已指导培养硕士研究生6名，其中多名学生获得校级一等奖学金、二等奖学金，国家奖学金，多名学生获在生命科学竞赛等竞赛中获奖。
